Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multiple birth defects and mental retardationInstead of sequencing the entire human genome, the new approach seq

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A protein known to be involved in a rare hereditary cancer syndrome may have a role in the regulation of liver stem cells and the development of liver cancerIn the August 15 issue of Genes & Development, a Massachusetts General Hospital (MGH) research team describes finding that the protein ca

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The boom in cancer biomarker investments over the past 25 years has not translated into major clinical successThe reasons for biomarker failures include problems with study design and interpretation, as well as statistical deficiencies, according to an article published online August 12 in The Jou

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Researchers in the Faculty of Medicine & Dentistry at the University of Alberta are one step closer to a treatment for a deadly diseasePulmonary arterial hypertension, which is high blood pressure in the lungs, currently has only a few treatment options but most cases lead to premature death.

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The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip – or the brain on a microchip – have been involved in the development of new technology that monitors brain cell activity at a Deve

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Along with skeletal muscles, it may be important to monitor heart function in patients with spinal muscular atrophy (SMAThese are the findings from a study conducted by Nationwide Children's Hospital and published online ahead of print in Human Molecular Genetics. This is the first study to report

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An ingredient in the venom of the "deathstalker" scorpion could help gene therapy become an effective treatment for brain cancer, scientists are reportingThe substance allows therapeutic genes — genes that treat disease — to reach more brain cancer cells than current approaches, accord

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New research finds that a protein that is often mutated in Huntington's disease (HD) plays an unexpected role in the process of neurogenesisThe research, published by Cell Press in the August 12 issue of the journal Neuron, provides new insight into HD pathology and has even broader implications f

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Melanoma is one of the less common types of skin cancer but it accounts for the majority of the skin cancer deaths (about 75 percentThe five-year survival rate for early stage melanoma is very high (98 percent), but the rate drops precipitously if the cancer is detected late or there is recurrence

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NORTH CHICAGO, IL – Michelle Hastings, PhD, Assistant Professor in the Department of Cell Biology and Anatomy, in the Chicago Medical School of Rosalind Franklin University of Medicine and Science, has been awarded a five-year $1.68 million grant from the National Institutes of Health to Dr.

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