Alzheimer's disease affects an estimated 27 million people worldwideIt is the most common form of age-related dementia, possibly the most feared disease of old age. There is no cure, and the available drugs only help to relieve symptoms without slowing progression of the disease. One of the charac

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A recent study found that rats with advanced fibrosis that were administered a short-term dose of losartan-M6PHSA had reduced liver inflammation and fibrosisThose animals treated with oral losartan alone did not experience a similar reduction in disease activity. Results of this study appear in th

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Spanish researchers determined that rats treated with recombinant ghrelin displayed a reduction in liver fibrosisGhrelin, a stomach hormone, reduced the amount of fibrogenic cells by 25% in the treated rodents. Research further showed ghrelin prevented acute liver damage and reduced oxidative stre

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A gene signature, first identified in mouse colon cancer cells, may help identify patients at risk of colon cancer recurrence, according to a recent study by Vanderbilt-Ingram Cancer Center researchersThe findings, published in the March issue of Gastroenterology, could help personalize treatments

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COLUMBUS, Ohio -- Reversing a protein deficiency through gene therapy can correct motor function, restore nerve signals and improve survival in mice that serve as a model for the lethal childhood disorder spinal muscular atrophy, new research showsThis muscle-wasting disease results when a child&r

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A new study published on bmj.com today casts doubt on recent claims that a human retrovirus known as XMRV is linked to chronic fatigue syndrome or ME (myalgic encephalitisThis is the third study to refute the original US study reporting the linkChronic fatigue syndrome is a debilitating condition

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A non-pathogenic bacterium is capable to trigger an autoimmune disease similar to the multiple sclerosis in the mouse, the model animal which helps to explain how human diseases work. This is what a group of researchers from the Catholic University of Rome, led by Francesco Ria (Institute of Multi

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A paper published online today in Molecular Cell proposes that Methyl CpG binding protein 2 (MeCP2) impacts the entire genome in neurons, rather than acting as a regulator of specific genesMutations in MeCP2 cause the autism spectrum disorder Rett Syndrome as well as some cases of neuropsychiatric

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HOUSTON -- A comprehensive drug development strategy that starts with extensive screening of potential targeting agents and then narrows down to a small-molecule prototype has yielded two potential drugs that block cancer-promoting pathways in novel ways, a team led by scientists at The University

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Stories of environmental damage and their consequences always seem to take place far away and in another country, usually a tropical one with lush rainforests and poison dart frogsIn fact, similar stories starring familiar animals are unfolding all the time in our own backyards — including g

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