Pancreatic ductal adenocarcinoma (the disease commonly referred to as pancreatic cancer) carries the worst prognosis of any cancerAs current treatments offer minimal benefit, entirely new approaches are needed. Given the success of local therapies, as opposed to intravenous systemic therapies, for

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Irvine, Calif. -- UCI immunologists have found that testing for increased levels of antibodies that inhibit energy production in neurons can detect axon and neuron degeneration in multiple sclerosis earlier than existing diagnostic toolsThe study, led by Yufen Qin, assistant professor of neurology

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AUSTIN, Texas -- Mutations in a gene known as "Fritz" may be responsible for causing human genetic disorders such as Bardet-Biedl syndrome, University of Texas at Austin developmental biologist John Wallingford and Duke University human geneticist and cell biologist Nicholas Katsanis have foundThe

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The brains of Alzheimer patients have high accumulations of the material beta-amyloid, which appear in the form of plaquesThe precursors of these plaques are believed to be the underlying cause of the nerve cell loss that leads to the disruptions in memory that characterize Alzheimer's disease. Th

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UCLA scientists have identified for the first time a cell-of-origin for human prostate cancer, a discovery that could result in better predictive and diagnostics tools and the development of new and more effective targeted treatments for the diseaseThe researchers, from UCLA's Jonsson Comprehensiv

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Researchers have found that an enzyme in the bacteria that causes cholera uses a previously unknown mechanism in providing the bacteria with energyBecause the enzyme is not found in most other organisms, including humans, the finding offers insights into how drugs might be created to kill the bact

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Often causing no symptoms in carriers of the disease, worldwide tuberculosis (TB) infects eight to ten million people every year, kills two million, and it is highly contagious as it is spread through coughing and sneezing"It's a global health disaster waiting to happen, even here in Canada, but t

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LA JOLLA, Calif. -- Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cellsWhat triggers cell death in the brain? According to a new study published by researchers at Sanford-Burnham M

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Scientists have successfully used "next generation sequencing" to identify mutations that may cause a rare and mysterious genetic disorderThe research, published by Cell Press on July 29th in the American Journal of Human Genetics, demonstrates that sequencing an affected individual's entire "exo

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Neuroscientists have long wondered how individual connections between brain cells remain diverse and "fit" enough for storing new memoriesReported in the prestigious science journal Neuron, a new study led by Dr. Inna Slutsky of the Sackler School of Medicine at Tel Aviv University describes what

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